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Finally in column we use the instrumental
2018-10-23

Finally, in column (5) we use the instrumental variable procedure, using the school inputs as instruments for school proficiency. We perform this exercise to examine whether there are omitted variables that are correlated with the proficiency and with wages, such as the students’ average (cell) abi
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Interestingly the response of F
2018-10-23

Interestingly, the response of F508del/Y1092X cells is almost double to that of F508del/G542X. While difference could be due to intrinsic responses of the F508del d-glucose from each of these donors, it is also plausible that the Y1092X mutation, given its localization towards the C-terminus of the
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br Materials and Methods br Results br
2018-10-23

Materials and Methods Results Discussion Our previous studies in mice with germline or induced ablation of SHIP1 expression suggested that chemical inhibition of SHIP1 in vivo might recapitulate genetic phenotypes that reduce the immune barrier to allogeneic HSCT and or enhance mobilization
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Previous smaller studies have found that
2018-10-23

Previous smaller studies have found that galanin screening in high-risk cohorts may be able to detect preinvasive pancreatic lesions amenable to interventions such as surgery (Verna et al., 2010; Canto et al., 2012), although the relatively low number of positive findings in screening studies and a
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In human cancer ABCB P gp ABCC multidrug resistance associat
2018-10-23

In human cancer, ABCB1/P-gp, ABCC1/multidrug resistance-associated protein 1 (MRP1), and ABCG2/breast cancer resistance protein (BCRP) are well-known causes of multidrug resistance to multiple chemotherapeutic agents, such as taxane and vinca alkaloids (Gottesman et al., 2002). Therefore, much effor
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br Future perspectives br Introduction Human organs are enor
2018-10-23

Future perspectives Introduction Human organs are enormously complex, involving specialized structures, cells, and tissues that interact to carry out unique functions essential to survival. Due to this complexity, it\'s no wonder that there is currently a lack of reliable model systems to reca
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br Introduction Major depressive disorder MDD is a leading
2018-10-23

Introduction Major depressive disorder (MDD) is a leading cause of disability (Whiteford et al., 2015). Amongst adolescents, point prevalence is 6–9% (Reivich et al., 2013), with a 25% lifetime prevalence by the end of adolescence (Kessler et al., 2001). Depressed adolescents demonstrate concurre
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It is unknown how rs SNP located in intron
2018-10-23

It is unknown how rs9838915 SNP located in intron 2 influences LV mass. KLF15 is expressed in cardiomyocytes and acts as a repressor of pathological cardiac hypertrophy (Wang et al., 2008; Fisch et al., 2007; Haldar et al., 2010; Leenders et al., 2012) through inhibition of the cardiac transcription
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The use of samples from
2018-10-23

The use of samples from a multicentre randomised placebo-controlled trial and the blinding of researchers to the treatment groups are strengths of the present study. However, the low sample number may prevent the detection of any small yet potentially important differences in the microbiomes of the
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br Author Contributions br Competing Interests br Introducti
2018-10-23

Author Contributions Competing Interests Introduction Colorectal cancer (CRC) is a common malignancy, and remains the second leading cause of cancer-related deaths in the Western countries (Siegel et al., 2015). Although cancer-related mortality associated with CRC have declined over the pa
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br Type Interferonopathies and Link to T D br
2018-10-23

Type 1 Interferonopathies and Link to T1D Type I IFNs and Type 1 IFN-Opathies: Implications for T cell Responses? As previously mentioned, T1D is historically characterized as a T-cell mediated disease. Here, we extend our discussions to suggest that the established IFN response that precedes
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Otamixaban Further information about the proposed
2018-10-23

Further information about the proposed 3D SEM surface reconstruction framework along with several experimental validations are explained in [2]. Based on the history of downloads (Fig. 2), the 3DSEM appears to be a popular dataset in the research community. In the near future, we would very much li
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The band at cm is rarely observed
2018-10-23

The band at 2510cm−1 is rarely observed. The most likely contributions can be associated to the dimer form of carboxylic acids, such as in solid state formic NVP-TNKS656 cost [10]. Furthermore, bands at ~2500cm−1 are observed also for saturated carboxylic dimers [11]. This gives an indication of a
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br Experimental design materials and methods br Data
2018-10-23

Experimental design, materials and methods Data The data reported include supporting information to the phylogenetic analyses of Franchi et al. [1]. They consist of transcript sequences, sequence alignments and comparisons of four apoptosis-related genes identified in the recently-obtained tra
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Bare frame structures as well as structures with
2018-10-23

Bare frame structures as well as structures with fully or partially unreinforced masonry infilled frames with or without openings have been analysed, in order to examine the influence of infill walls. A lot of parameters have been considered for each case. Infill panels are either 0.15 or 0.25m thic
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