• CXCL has been previously identified as an estrogen regulated

  2018-10-24

  

  CXCL12 has been previously identified as an estrogen-regulated gene in estrogen receptor (ER)-positive ovarian and breast cancer TIC10 Supplier (Jaerve et al., 2012). Here we show that in the endometrium, E2 significantly increased CXCL12 expression, suggesting a mechanism by which stem cells are r

• br Materials and methods br Author

  2018-10-24

  

  Materials and methods Author Responsibilities Disclosure Study sponsor Acknowledgments We thank Lucy Brown and Alexander Spalla from the Analytical Cytometry Core, Ricardo Zerda and Zhuo Li from the Electron Microscopy Core, and Dr. Xiwei Wu and Charles Warden from the Integrative Gen

• gadobutrol i iPSC colonies displayed a typical

  2018-10-24

  

  i10984 iPSC colonies displayed a typical ES-like colony morphology (Fig. 1B). Immunocyto-chemical analysis revealed expression of transcription factors OCT4 and SOX2, and surface markers SSEA4 and TRA-1–81, characteristic of pluripotent stem gadobutrol (Fig. 1B). The iPS cells exhibited a normal ka

• Next to the significant evidence that CpG methylation of

  2018-10-24

  

  Next to the significant evidence that CpG methylation of the HLA-G promoter is important for the transcriptional activity of the gene (Moreau et al., 2003; Mouillot et al., 2005), HLA-G c-met inhibitor is also post-transcriptionally regulated by the 3′UTR. Several polymorphic sites in the 3′UTR hav

• hCNS SCns migration was extensive detected by week following

  2018-10-24

  

  hCNS-SCns purchase Brefeldin A was extensive, detected by 1 week following transplantation, and altered by the injured microenvironment. Injury induced transplanted hCNS-SCns to remain closer to the SCI epicenter, which has been reported in other cases of CNS trauma and degeneration (Connor et al.,

• We speculate that in vivo

  2018-10-24

  

  We speculate that in vivo, serum GH of pituitary and placental origin may be responsible for the expansion of mammary stem/progenitor adenylate cyclase during developmental windows when the mammary gland grows isometrically (intrauterine life, childhood). In adulthood, when GH secretion from the pi

• The molecular mechanisms controlling the establishment of im

  2018-10-24

  

  The molecular mechanisms controlling the establishment of imprinting at the GNAS cluster and leading to the methylation defects in PHP1B are mostly unknown, in part because of a paucity of suitable animal models and lack of accessible Gsα-imprinted human tissues. During the murine embryonic developm

• br Introduction Pluripotent stem cells can generate

  2018-10-24

  

  Introduction Pluripotent stem cells can generate all cell types of the body and hold great potential for transplantation medicine and the study of early development. Pluripotency arises in the inner cell mass of blastocyst-stage embryos during formation of the epiblast, and both human and mouse b

• br Introduction Advances in stem cell based therapies

  2018-10-24

  

  Introduction Advances in stem-cell-based therapies may help overcome CNS disorders such as spinal cord injury (SCI). Transplantation of neural stem/progenitor meclizine hcl (NS/PCs) has yielded beneficial effects and improved functional recovery in SCI animal models (Cummings et al., 2005; Hofste

• br Author Contributions br Acknowledgments br Introduction N

  2018-10-24

  

  Author Contributions Acknowledgments Introduction Neurons in the CNS are particularly sensitive to injury and degenerative conditions that frequently result in cell death. Although adult neurogenesis persists in restricted 5-aminosalicylic acid areas (Gage, 2000; Hsieh, 2012; Kriegstein and

• It has furthermore been speculated whether

  2018-10-24

  

  It has furthermore been speculated whether Sca-1 plays a role in stem cell self-renewal. Thus, some experiments with Sca-1 −/− knock-out mice investigating hematopoietic and mesenchymal progenitor Bindarit have pointed to a role for Sca-1 in self-renewal (Bonyadi et al., 2003; Ito et al., 2003). Ho

• notch signaling pathway Importantly STS and STS have been sh

  2018-10-24

  

  Importantly, STS1 and STS2 have been shown to have overlapping functions (Carpino et al., 2002; Carpino et al., 2004). However, although expansion of LSK, increased serial colony growth, and hyperphosphorylation of FLT3 were largely attributable to the loss of STS1, further loss of STS2 strengthened

• Our study showed that neurite length

  2018-10-24

  

  Our study showed that neurite length and the ratio of apoptotic wst-1 in FALS- and FUSH517D/H517D iPSC-derived neurons were the same as in control motor neurons. With several stresses especially in glutamate treatment, however, FALS- and FUSH517D/H517D HB9-positive motor neurons exhibited shorter n

• These data are in agreement with prior studies

  2018-10-24

  

  These data are in agreement with prior studies demonstrating that hyaluronan levels play a critical role in determining the site of HSC lodgment/engraftment following transplantation (Avigdor et al., 2004; Ellis et al., 2007, 2009, 2011; Nilsson et al., 2003), and that HSC exhibit preferential engra

• At a global level the analysis of DNA

  2018-10-24

  

  At a global level, the analysis of DNA-methylation profiles provides important insights into molecular and cell growth characteristics of PSC that would otherwise be difficult to identify. Reprogramming-associated variations in X-linked CpG methylation is of particular interest because of the comple

16223 records 1077/1082 page Previous Next First page 上5页 10761077107810791080 下5页 Last page