• Despite these assay limitations the results of this survey p

  2018-10-22

  

  Despite these assay limitations, the results of this survey provide a snapshot of the prevalence of protozoan oocyst species of human health concern in domestic and imported leafy greens in Canada, which may assist in developing food safety guidelines, pre- and post-harvest control measures, and ris

• Introduction Scientific evidence suggests that the

  2018-10-22

  

  Introduction Scientific evidence suggests that the consumption of whole grain foods reduces the risk of heart disease, type 2 diabetes, obesity and certain types of cancer [1–4]. All over the world, the number of people affected by these diseases is increasing at a high rate. For example, the preva

• The latest studies have found that vitamin C and vitamin

  2018-10-22

  

  The latest studies have found that vitamin C and vitamin E have synergistic antioxidant effect. Betancor et al. [42] have reported that the combinatorial application of vitamin C and vitamin E can synergistically increase mRNA expression level of catalase (CAT), SOD and GSH-Px in Largemouth Bass juv

• Damascenone Fig and ionone Fig

  2018-10-22

  

  β-Damascenone (Fig. 3) and β-ionone (Fig. 4a) are two representative aromas formed from carotenoid degradation. β-damascenone has an apple-like flavor and has an extremely low threshold in water (0.002ppb). It was first identified in Bulgarian rose oil in 1970 [9] and is an essential odor in black t

• Owing to their extremely complex anatomical structures in ma

  2018-10-22

  

  Owing to their extremely complex anatomical structures in mammals and humans, identification of stem cell niches has proven to be difficult (Li and Xie, 2005). Consequently, in vivo studies to elucidate signals that regulate stem cell activity suffered from this circumstance. Medical application of

• Our xeno free culture conditions made single cell

  2018-10-22

  

  Our xeno-free culture conditions made single cell passaging possible, and we could also generate EBs from single cell suspensions. Although both hESC lines retained a normal karyotype, we did observe an accumulation of a chromosomal abnormality in one of our cultures. After 13 passages under xeno-fr

• One approach to generate specific cell populations is to dir

  2018-10-22

  

  One approach to generate specific cell populations is to direct PSCs toward a desired cell type by sequential progression through intermediate cell populations, mimicking the stages of embryonic development. Monolayer differentiation approaches allow homogeneous accessibility of Cy3.5 hydrazide to

• br Experimental Procedures br Acknowledgments This work was

  2018-10-22

  

  Experimental Procedures Acknowledgments This work was supported by BONFOR/Gerok Scholarships O-137.0015 (to B.V.S.), Ruediger Foundation grants (to B.V.S.), State Scholarship Fund/Chinese Scholarship Council 2008627116 (to Z.L.), NIH – National Eye Institute 5R01EY022079-02 (to S.T.), and NYSD

• Last but not least the differentiation

  2018-10-22

  

  Last, but not least, the differentiation method described here can be refined to be fully defined and xeno-free by substituting human serum albumin (HSA) present in RegES− medium with recombinant HSA (He et al., 2011) and using a higher certificate, xeno-free version of CnT-30 medium (CELLnTEC Advan

• Fibroblasts can be directly reprogrammed into neurons Vierbu

  2018-10-22

  

  Fibroblasts can be directly reprogrammed into neurons (Vierbuchen et al., 2010), cardiomyocytes (Ieda et al., 2010), and NSCs (Han et al., 2012) using tissue-specific combinations of transcription factors. However, the pluripotent reprogramming cocktail of Oct4, Sox2, Klf4, and Myc can also convert

• The recovery of ExEn outer layer

  2018-10-20

  

  The recovery of ExEn outer layer and down-regulation of pluripotent genes in mutant EBs grown in medium supplemented with BMP4 indicate that the failure of Pelo-null cells to down-regulate pluripotency-related genes in EBs is not a result of cell-autonomous effect, but rather to failed signals from

• Taken together we conclude that Lats

  2018-10-20

  

  Taken together, we conclude that Lats may regulate adult cardiomyocyte hypertrophy independent of Yap or Tead1. Rather than controlling cardiac hypertrophic growth, the canonical Hippo/Yap pathway is crucial for regulation of cardiomyocyte survival in the adult heart. This parallels the findings in

• br Materials and methods br Results

  2018-10-20

  

  Materials and methods Results Discussion riPSCs are typically generated and cultured on MEF feeders (Liu et al., 2008). Feeders are sufficient to support rhesus iPSC long-term maintenance. However, this approach is too labor intensive for large-scale culture. Optimization of this culture sy

• br Materials and methods br Results br

  2018-10-20

  

  Materials and methods Results Discussion Obesity results when caloric intake exceeds energy expenditure, with an increase in adipocyte size or adipocyte number (Bjorntorp, 1974; Faust et al., 1978; Johnson et al., 1971, 1978; Yu et al., 1997). In the context of adipogenesis, development app

• In this study we demonstrated that unrelated

  2018-10-20

  

  In this study, we demonstrated that unrelated allogeneic human MSCs supported a LSC phenotype in a largely quiescent state in a long-term vitro culture system. We then confirmed the persistence of LIC after 6weeks co-culture with MSCs using the NSG mouse xenotransplant model. Our results also reveal

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