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Nodal Activin signaling is an
2018-10-29
Nodal/Activin signaling is an evolutionarily conserved signal transduction pathway, and plays critical roles in the maintenance and differentiation of hESCs. Nodal and Activin (Activin A and Activin B [Thompson et al., 2004]) are members of the transforming growth factor beta (TGFβ) superfamily, and
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The increasing number of studies focusing on regenerative me
2018-10-29
The increasing number of studies focusing on regenerative medicine and stem cell transplantation is being accompanied by the development of techniques using many types of nanoparticles. The combination of nanotechnology with stem cell research may be able to address some challenges in this research
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However as their origin remains
2018-10-29
However, as their origin remains unclear, here, we aimed to determine their ancestor(s) in the skeletal muscle. The skeletal muscle is highly vascularized and contains a variety of mononucleated cells, including blood, endothelial, fibroblasts, myofiber satellite, immune, and pericytes. Pericytes ca
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Herein to trace the differentiation and analyze human ES or
2018-10-29
Herein, to trace the differentiation and analyze human ES or iPS cell-derived hepatocytes, we carried out gene targeting of a reporter transgene to the ALB locus and established ALB/monomeric Kusabira orange1 (mKO1) knock-in (ALB/mKo1) hES and hiPS cell lines, and report here the use of these knock-
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br Results br Discussion Recent advances enabling the prospe
2018-10-29
Results Discussion Recent advances enabling the prospective isolation of mouse satellite enzyme substrate have facilitated mechanistic analyses of their myogenic function. For example, the ability to clonally sort satellite cells with high purity made possible the demonstration that these cell
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In this study ASC transplantation
2018-10-26
In this study, ASC transplantation was able to counteract the appearance of coagulopathy and encephalopathy, which are the two main clinical features of ALF (Lee and Stravitz, 2011). Transplanted animals had levels of transaminases, INR and ammonia comparable to those of healthy control rats and did
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br Lineage tracing tools for investigating stem cell
2018-10-26
Lineage tracing tools for investigating stem cell biology The investigation of cell lineage involves labeling Wnt-C59 of interest, then tracing the destiny of their progeny. The reliance on the presence of cell markers alone to infer the origin or fate of a cell population is fallible, as marker
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br Acknowledgments This study was
2018-10-26
Acknowledgments This study was funded by a grant provided by the Royan Institute. We thank Mr. Ehsan Janzamin for his unlimited assistance in the Flow Cytometry Laboratory, Dr. Abass Piryaei and Leila Sattarian in the Histology Laboratory, Mr. Chehrazi for statistical analysis, and Miss Saloomeh
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ap4 Supplier Introduction The pluripotency promoting role of
2018-10-26
Introduction The pluripotency-promoting role of the reprogramming factors OCT4, SOX2, KLF4, and MYC (OSKM) is widely appreciated. However, these reprogramming factors also promote expression of non-pluripotency genes. For example, OCT4 (Pou5f1) directly promotes expression of genes important for mo
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The stationary solution of the
2018-10-26
The stationary solution of the system of equations (1) has the form: where Since the intermode interval Δ0 = 0.05, for calculation convenience, similarly to the supposition made in [6], let us assume that the axial mode of the resonator corresponding to the maximum gain at the 1064.15 nm wavelen
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Introduction Currently organic materials are increasingly us
2018-10-26
Introduction Currently, organic materials are increasingly used in micro- and optoelectronics for creating photo- and light-emitting diodes, sensors, RFID tags, and other devices. There is a particular interest in compounds that may have some advantages over classic semiconductors, as the methods f
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br Distinguishing features of and selected tensions within a
2018-10-26
Distinguishing features of, and selected tensions within, a model-based perspective A model-based perspective emphasizes the processes producing outcome variation, and observed data are used to characterize that data-generating process. This is the majority perspective in statistical textbooks, i
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This research adds to the
2018-10-26
This research adds to the body of evidence showing the long-term health benefits of years of schooling. A recent review of the evidence on the impact of education on health finds health benefits arise from receiving high quality education (Cohen & Syme, 2013). Relating education and literacy, qualit
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kit inhibitor br Acknowledgements This work was supported by
2018-10-26
Acknowledgements This work was supported by NIH grants 1R01MD006064 and 1R21HD066312 (Dr. Osypuk, PI), and the Minnesota Population Center grant P2C HD041023. Funders did not have any role in design or conduct of the study; collection, management, analysis, and interpretation of the data; or prep
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br Conclusion br Acknowledgements br Introduction About wome
2018-10-26
Conclusion Acknowledgements Introduction About 265,000 women served in the U.S. military during the Vietnam era, with as many as 11,000 deployed to the Vietnam theater of operations (precise figures are not available) (Thomas, Kang, and Dalager, 1991; http://www.vietnamwomensmemorial.org/vw
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