• br Introduction Foundational cell fate reprogramming

  2018-11-08

  

  Introduction Foundational cell fate reprogramming studies revealed ectopic expression of pluripotency-associated transcription factors (TF) OCT4, SOX2, KLF4, and c-MYC (OSKM) or OCT4, SOX2, NANOG, LIN28 (OSNL) in human fibroblasts (hFibs) cultured in pluripotent supportive conditions was sufficie

• Pluripotent stem cell marker analysis iPSCOCT express plurip

  2018-11-08

  

  Pluripotent stem cell marker analysis: iPSCOCT4 express pluripotent markers SSEA3, TRA-1-60, OCT4, NANOG and SOX2 as measured by flow cytometry (Fig. 1E). Pluripotent functionality: iPSCOCT4 are capable of three germ layer differentiation capacity as assessed by in vivo teratoma assay (Fig. 1F).

• In the current study we compared two different genetic backg

  2018-11-08

  

  In the current study, we compared two different genetic backgrounds on the induction and maintenance of multipotency by generating clonal iNSC lines from two distinct mouse strains (C57BL/6 vs. C3H). Clonal iNSC lines from distinct genetic backgrounds exhibited the distinct levels of conversion effi

• br Author contributions br Conflict of interests br Acknowle

  2018-11-08

  

  Author contributions Conflict of interests Acknowledgments We thank Dr. Wenying Liu for her help with the initial setup of the electrospinning and Mr. Xiyu Li for his assistance with SEM. We also thank Emory Children\'s Pediatric Research Center Flow Cytometry Core and Animal Physiology Cor

• Recently human umbilical cord hUC has been investigated

  2018-11-08

  

  Recently, human umbilical cord (hUC) has been investigated as a source of pten inhibitor with stem/progenitor cell properties. hUC is a desirable source of stem/progenitor cells as it is routinely discarded after delivery, collection is non-invasive and an abundant number of cells are present in cor

• P and p are cyclin dependent kinase inhibitors that play

  2018-11-08

  

  P21 and p16 are cyclin-dependent kinase inhibitors that play important roles in cell-cycle regulation and tumor suppression (Poole et al., 2004; Shapiro et al., 1998), and both are highly expressed upon senescence in MSCs. Knockdown of p21 in late-passage MSCs increases stem cell properties, includi

• br Materials and methods br Results

  2018-11-08

  

  Materials and methods Results Discussion NPY is one of the most common neuropeptides in mammals, and it is abundant in the central and peripheral nervous system. Recent studies have indicated that the neuropeptides SP and NPY can regulate many biological activities in BMSCs and MC3T3 Wnt ag

• Most remarkably we identified Nppb Bnp a well

  2018-11-08

  

  Most remarkably, we identified Nppb (Bnp), a well-studied marker in cardiovascular disease, as a novel putative Shox2 target gene. This gene was analyzed as working myocard marker and turned out to be significantly upregulated in Shox2 SAN-like Batimastat and in right atrial tissue of Shox2-KO embr

• br Experimental Procedures br Acknowledgments br Introductio

  2018-11-08

  

  Experimental Procedures Acknowledgments Introduction Germ Y27632 are the only cells that continue to be reprogrammed throughout their lifetime in order to transfer genetic information to subsequent generations (Sasaki and Matsui, 2008). Germ cells have unique characteristics such as genome-

• clozapine-n-oxide br Results br Discussion The cognitive def

  2018-11-08

  

  Results Discussion The cognitive deficits associated with prenatal VPA exposure might not due solely to the reduced neurogenesis with the abnormal neuronal morphology in the hippocampus, and there is a possibility that the low freezing responses in fear associative tests were contributed by th

• The Douay group reported that when adult HSC derived

  2018-11-07

  

  The Douay group reported that when adult HSC-derived mature erythroblasts were peripherally injected into the donor, at least half could survive in circulation for as long as 26 days (Giarratana et al., 2011). However, these in vitro expanded mature erythroblasts did not accumulate in a specific org

• This study has some limitations that should be noted First

  2018-11-07

  

  This study has some limitations that should be noted. First, we did not obtain information about income, which is thought to be an important component of SES (Winkleby, Jatulis, Frank, & Fortmann, 1992). This may confound the relationship between physical assaults and depression. Second, the sample

• A study on intracerebral EEG recording during

  2018-11-07

  

  A study on intracerebral EEG recording during sleep documented a dissociation of regional EEG activities during a parasomnia episode, illustrating how the guanidine hydrochloride phenomenon of “local sleep” can be the substrate for clinical dissociated states [17]. In this study, a young adult male

• eicosapentaenoic acid Columns in Table present the

  2018-11-07

  

  Columns 1–6 in Table 4 present the estimated results for the dependent variable average Prova Brasil test scores in Portuguese for 5th grade students in basic education. Each column presents the results of an estimator (LS, FE and RE) with the matching and additional covariates. All the ATT measurem

• br Materials and Methods br Results br Discussion There

  2018-11-07

  

  Materials and Methods Results Discussion There is an increasing awareness of the central role endothelial dysfunction plays in CV disorders. Low numbers of EPC-CFUs strongly correlate with endothelial dysfunction (Werner et al., 2007) and are associated with a high Framingham risk score for

14066 records 919/938 page Previous Next First page 上5页 916917918919920 下5页 Last page