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br Introduction Accounting educators and professional accoun
2020-12-08

Introduction Accounting educators and professional accounting organizations have speculated that advanced placement (AP) may be an effective tool for recruiting high-quality students into accounting education programs (Deines, Bittner, & Eichman, 2012; The Pathways Commission, 2012), and it is n
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br Making the BN Cox
2020-12-08

Making the BN-Cox model computationally efficient One of the challenges to applying the BN-Cox model is an exponential growth of the conditional probability tables (CPT) corresponding to the survival variables, as the number of risk factors increases [22]. When the number of risk factors is high,
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Although CK phosphorylated Msn as well as
2020-12-08

Although CK2 phosphorylated Msn4 as well as Msn2 (Fig. 1A), the two CK2-dependent phosphorylation sites in Msn2 are not conserved in Msn4. Thus, Msn2 and Msn4 might be differently regulated by CK2-dependent phosphorylation. Msn2 and Msn4, which have 41% identity and similarity in size and amino Febu
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The first mammalian mutation linked
2020-12-08

The first mammalian mutation linked to CR was identified in golden hamsters (Mesocricetus auratus). The mutation was an autosomal allele first described in the late 1980s [8] and was identified using positional cloning [9]. These animals displayed a shortened period length (20h in homozygous animals
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br Conflict of interest br Acknowledgements This study was
2020-12-08

Conflict of interest Acknowledgements This study was supported by the National Natural Science Foundation of China (No.31571839), the Chinese Ministry Program for New Century Excellent Talents in University (NCET-12-0865), and Special Fund for Agro-scientific Research in the Public Interest (N
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Cap Firefly Luciferase mRNA australia In this study the ASTM
2020-12-07

In this study, the ASTM C1260 and ASTM C1567 test methods were followed to conduct the ASR tests. Three mortar bars were prepared using three types of RHA (600-RHA, 150-RHA, and 44-RHA) and CFA. To prepare the mortar bars, the OPC was replaced by each type of RHA for 10% and 20%, respectively by wei
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Quantum dots QDs which exhibit excellent fluorescence quantu
2020-12-07

Quantum dots (QDs), which exhibit excellent fluorescence quantum yields (QYs), high extinction coefficients and size-tunable narrow emission have highly attracted great interest in various applications such as in solar cells, sensors, and bioimaging [16], [17], [18], [19], [20]. However, QDs suffere
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br Materials and methods br Results br Discussion In additio
2020-12-07

Materials and methods Results Discussion In addition, the responses of CYP450s induced by metalaxyl are species-specific in the four cells. For example, metalaxyl lead to induction of CYP1A1, CYP1A2, and CYP2B1 in HepG2 cells, CYP1A2 and CYP2B1 in H4IIE cells, CYP1A1 and CYP2B1 in LMH cells
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In some cases more than one CYP enzyme may be
2020-12-07

In some cases, more than one CYP450 enzyme may be involved in the metabolism of a drug, and an Eadie–Hofstee plot is usually more reliable for assessing the involvement of multiple UK 356618 (Bu, 2006). Therefore, we first plotted the Eadie–Hofstee curves and observed their shape to determine the k
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br EBV Infection Epstein Barr virus EBV human herpesvirus
2020-12-07

EBV Infection Epstein–Barr virus (EBV, human herpesvirus 4) was discovered 50 years ago, when Epstein, Achong, and Barr used electron microscopy to identify viral particles in Burkitt's lymphoma cells. It belongs to the lymphocryptovirus (LCV) genus of the gammaherpesvirus subfamily (Fig. 1A). Th
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br Materials and methods br Results
2020-12-07

Materials and methods Results Discussion Regardless of obvious beneficial effects of GC on acceleration of foetal lung and cardiomyocytes maturation (Kamath-Rayne et al., 2012; Rog-Zielinska et al., 2015), the current study revealed that GC exposure during late pregnancy induces IR and alte
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Dihydrofolate reductase DHFR is an excellent molecular
2020-12-07

Dihydrofolate reductase (DHFR) is an excellent molecular target for this study because it has been and is currently studied by using different molecular modeling techniques [6], [7], [8], [9]. Kerrigan et al. have reported an interesting review about recent progress in molecular dynamics simulations
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br Type II NAD P H
2020-12-07

Type II NAD(P)H Dehydrogenases in Fungi Fermentative YeastSaccharomyces cerevisiaeBecause S. cerevisiae is a facultative YC 1 yeast capable of meeting its energy requirements with ATP generated by fermentation, only relatively few mitochondrial proteins are essential for cell viability. The mito
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Films treated with Diaz ES
2020-12-07

Films treated with Diaz-ES-VWFIIINle but not exposed to UV light supported only slight platelet deposition, suggesting that passively-bound peptides were removed under shear. However, treatment with Diaz-ES-VWFIIINle and UV restored platelet surface coverage to about 50% of the level on native colla
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A small subset of compounds
2020-12-07

A small subset of compounds composed the 5-[1,2,4]triazino[5,6-]indole cluster (). This series of compounds was characterised by a central heterocyclic core with an R1 alkyl amine chain, required for potency (. , , and ), with preference for morpholine over piperidine (. ). The scaffold can be subs
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