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In this study Oncomine GEO and
2021-01-15

In this study, Oncomine, GEO and TCGA databases were used to analyze the expression of UBE2S gene in HCC and normal liver tissues to determine the relationship between UBE2S expression and prognosis of hepatocellular carcinoma. The potential function of UBE2S in HCC was analyzed by screening UBE2S c
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br Acknowledgements We thank Dr James Ritchie and his dedica
2021-01-15

Acknowledgements We thank Dr. James Ritchie and his dedicated staff (Deptartment of Pathology, Emory University) for performing measures of serum VPA levels; Sumitomo Pharmaceuticals (Osaka, Japan) for the generous donation of DOPS, which is required for breeding Dbh −/− mice; Pfizer (Sandwich, K
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Experimental studies offer a means of developing an
2021-01-15

Experimental studies offer a means of developing an empirical basis for the development of forensic protocols in the investigations of specific crime types [12]. Such an evidence A769662 mg for ICST cases will help enable the identification of situations when there is likely to be recoverable DNA f
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This study had some limitations First a small number of
2021-01-15

This study had some limitations. First, a small number of HP patients were enrolled because of the extreme rarity of this disease, which may have caused some selection bias. Yokoseki et al., found no increase in Th2 cytokines, such as IL-4, in IHP patients (Yokoseki et al., 2014). The sensitivity of
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Increased knowledge about CRC pathogenesis has
2021-01-15

Increased knowledge about CRC pathogenesis has provided new and remarkable treatments beyond the classical options of surgery, radiation and chemotherapy [11]. Despite these advances, chemotherapy remains the most important element of anti-cancer therapy. Chemotherapy, when initiated, is generally e
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Furthermore our sample preparation uses a simple isolation p
2021-01-15

Furthermore, our sample preparation uses a simple isolation procedure. Numerous CYP450 phenotyping methods employed extensive extraction procedures for sample preparation such as dual liquid extraction or solid phase extraction which are costly and time consuming [10], [17], [18], [19], [20], [23],
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Several highly selective COX inhibitors coxibs
2021-01-15

Several highly selective COX-2 inhibitors (coxibs) have been reported and marketed [6], including celecoxib [7] and etoricoxib [8] (Fig. 1). Even though these drugs produce less ulceration than conventional NSAIDs, coxibs still produce significant gastric and cardiovascular side effects due to the d
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br Materials and methods br
2021-01-15

Materials and methods Results and discussion Conclusions Given that the activity of anti-plant virus compounds is related to host tobacco, virus, and compounds, we determined the effect of anti-CMV compound NNM on defense enzyme activity and chlorophyll index in tobacco, and we used RIB as
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Curcumin is a polyphenol extracted from turmeric which is
2021-01-15

Curcumin is a polyphenol extracted from turmeric, which is commonly used as a spice and food-coloring agent in many cultures [9]. Curcumin possesses anti-inflammatory, antioxidant, and cancer-preventive properties [10], [11], [12]. In addition to these well-known effects, consuming curcumin may bene
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br Discussion Variable estradiol effects on cell proliferati
2021-01-15

Discussion Variable estradiol effects on cell proliferation have been reported according to animal species, tissues, and type of estrogen receptor [16,21,22,[29], [30], [31]]. In the kidney, 17βE was found to increase [3H]-thymidine incorporation in primary rabbit kidney proximal tubule BTS suppl
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Damage of PE HD due to
2021-01-15

Damage of PE-HD due to both mechanisms is usually considered to emerge from a local stress concentration in the material, leading to the initiation of a crack, which subsequently propagates further through the material, and finally leads to macroscopic failure. In this process, crack growth occurs o
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The new ESC guidelines incorporate data
2021-01-15

The new ESC guidelines incorporate data from a network meta-analysis of 100 studies confirming that new-generation drug-eluting stents (DES) improve survival compared with medical treatment, although this has not been demonstrated in any individual study. REVASCULARIZATION IN NON–ST-ELEVATION ACU
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br Thy nephritis is one of the most
2021-01-14

Thy1.1 nephritis is one of the most commonly used models to study the course of immunoglobulin A and other mesangioproliferative nephropathies. To date, most of the studies have focused on mesangial and, to a lesser extent, endothelial cell recovery following capillary damage, whereas data concern
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br Results and discussion br Conclusion Recent studies showe
2021-01-14

Results and discussion Conclusion Recent studies showed that EGFR signaling is involved in inflammatory response in several inflammatory conditions. The normal inflammatory macrophage azidothymidine show EGFR-dependent production of inflammatory mediators. Nevertheless, the development of EGFR
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br Experimental Procedures br Author Contributions
2021-01-14

Experimental Procedures Author Contributions Acknowledgments Introduction In addition to the HLA region numerous other loci have shown association with type 1 diabetes risk [1], and susceptibility caudatin have been identified in many of these regions [2]. How these genes exert their fu
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