• The serotonin transporter gene encodes an

  2021-06-21

  

  The serotonin transporter gene () encodes an integral membrane protein that transports serotonin from the synaptic spaces into the presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent way. This protein is a target of psychomotor stimulants

• The BDNF Val Met polymorphism

  2021-06-21

  

  The BDNF Val66Met polymorphism is also associated with decreased dendritic arborization and impaired long-term potentiation [25]. This is particularly important for the hippocampus, and healthy individuals with a BDNF Val66Met allele have decreased hippocampal volumes [30]. Hippocampal atrophy is co

• In SLO permeabilized human sperm the AR elicited

  2021-06-19

  

  In SLO-permeabilized human sperm, the AR elicited by calcium, persistently active Arf6 [41] and Rab3A, 8-pCPT-2′-O-Me-cAMP [8], diacylglycerol and a non-hydrolyzable analog [35], is sensitive to the PLC blocker U73122. Furthermore, 8-pCPT-2′-O-Me-cAMP elicits a calcium signal in non-permeabilized sp

• The contribution of local ETA and

  2021-06-19

  

  The contribution of local ETA and ETB receptors towards heat hyperalgesia induced by inoculation of XC tumor Cucurbitacin B in the paw of mice has been demonstrated by Baamonde and colleagues (Baamonde et al., 2004). Furthermore, using neuropathic and inflammatory nociception models, several studie

• br Material and methods br Results br

  2021-06-19

  

  Material and methods Results Discussion Isolated SGX-523 have several potential advantages over other in-vitro approaches, such as expression of properties similar to their site of origin including the possibility of bidirectional transmembrane transport and exposure. Furthermore, they mak

• br Introduction The Epstein Barr

  2021-06-19

  

  Introduction The Epstein–Barr virus induced gene 2 (EBI2 also known as GPR183) is a G protein-coupled seven-transmembrane (7TM) receptor that is predominantly expressed in B and T cells [1,2]. It regulates the trafficking of Pyridoxine HCl within lymphoid tissues and is highly important for the g

• br Conclusion As far as

  2021-06-19

  

  Conclusion As far as we know, this work constituted the first use of silver nitrate staining and sequential FISH in V. vinifera. This technique allowed the unequivocal identification of Ag-NORs and corresponding rDNA loci. Besides, silver nitrate staining and sequential FISH may bring new insight

• Another important issue in biosensors is

  2021-06-19

  

  Another important issue in biosensors is to design a simple and potable detection strategy to meet the requirement of the point-of-care (POC) test applications. According to the recent research, by using invertase UNC 0646 for hydrolyzing sucrose into glucose, the range of personal glucometer has b

• br Materials and methods br Results br

  2021-06-19

  

  Materials and methods Results Discussion The first DGAT1 gene was described in the mouse in 1998 [28], and a few years later DGAT2 was identified from the oleaginous fungus Mortierella ramanniana[29]. Although both of them are known as the primary enzymes for de novo TAG biosynthesis, they

• Carmustine synthesis With regard to the DGATs we have

  2021-06-19

  

  With regard to the DGATs, we have found that the majority of algal species encode at least one DGAT1, although it appears to be absent from Ostreococcus and Micromonas, as is the case for yeast, S. cerevisiae. More surprising is the presence of multiple DGAT2 genes in algae, with the exception of C.

• br Cytokines and NK cells

  2021-06-19

  

  Cytokines and NK cells Combined effects of cytokines and other stimuli on NK cell function Cytokine-stimulated NK 777 symbolism receptor have enhanced capacity to kill tumor cells. However, usually, individual cytokines do not seem to be sufficient for full activation, proliferation, survival

• br Experimental br Results and discussion

  2021-06-18

  

  Experimental Results and discussion Fig. 2 shows schematically the fundamentals of the developed HRP-P4-(P4)-anti-P4-Protein-G-MBs/SPCE immunosensor. Oriented immobilization of anti-P4 was accomplished onto Protein G-MBs due to the Protein G binding ability with the Fc region of many mammals i

• Emi protein consists of an N terminal regulatory region and

  2021-06-18

  

  Emi2 protein consists of an N-terminal regulatory region and a C-terminal functional region. The C-terminal region contains a destruction box (D-box), which likely competes with APC/C substrates (including cyclin B) for APC/C binding, and a zinc-binding region (ZBR), which somehow inhibits APC/C ubi

• br Acknowledgements br A subgroup of pediatric solid neoplas

  2021-06-18

  

  Acknowledgements A subgroup of pediatric solid neoplasms, collectively referred to as small round cell tumors (SRCTs) of childhood, demonstrates undifferentiated small round cell morphological characteristics. The SRCTs include neuroblastomas, lymphomas, and several bone and soft tissue sarcoma

• Results are expressed as mean s e m Paired

  2021-06-18

  

  Results are expressed as mean±s.e.m. Paired or unpaired Student's t test was used for comparisons between 2 groups and one-way ANOVA followed by Bonferroni's post-test for more groups. Statistical significance was assigned if p Results and discussion Variations in [Ca2+]i in cardiomyocytes loaded

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