Archives
Serology for HIV toxoplasmosis and syphilis
Serology for HIV, toxoplasmosis and syphilis was done since these conditions are not rare in our context. Extra nodal manifestations in the head and neck are significantly more common in SHML patients with immunological abnormalities [4,5].
The therapy for RDD is yet to be determined because of the rarity of the disease and its propensity for spontaneous remission. Excision, parp apoptosis pathway therapy, chemotherapy and systemic steroids have all been tried by different authors [10]. The first line of interventional therapy to be considered is gross total excision along with adjuvant steroids or more aggressive chemotherapy or radiotherapy when necessary [8].
Treatment depends upon the patient individually and is planned after thorough testing to determine the extent of disease. Ideal treatment, however, has not been established, and there is no ongoing clinical trial [11].
It is believed that 70%–80% of patients recovered from symptoms without treatment, although they may have alternating episodes of exacerbation and remission of symptoms for a long period of time, some patients with severe or persistent disease or cases with risk of organ dysfunction may require treatment with surgery, steroids, and/or chemotherapy. radiation therapy is rare to be used. Chemotherapy may include vinblastine, 6-MP, and methotrexate. Thalidomide or Gleevec. The ultimate goal of an overall treatment plan is to use as little treatment as possible to keep the disease under control and preserve quality of life [12].
This disease not usually threats life or induces organ dysfunction. [13] 5%–10% of patients show progress of the disease that may damage tissue. However, for most patients, the disease is self-limited, and the outcome is good [13,14].
Conclusion